Micro deletion testing
AZ a,b,cmicrodeletion testing for Azoospermia (blood PCR)
Microdeletions in the Y chromosome have been found at a much higher rate in infertile men especially in those with severe OAT or non-obstructive azoospermia. Much study has been focused upon the "Azoospermia Factor Locus" (AZF), at Yq11. A deletion of AZFa and AZFb is associated with near zero sperm in theman. while if there is a specific partial deletion of AZFc called gr/gr deletion, there is some chances of recovering sperm in testicular biopsy specimens in such men undergoing tese or micro tese.
Additional genes associated with spermatogenesis in men and reduced fertility upon Y chromosome deletions include RBM, DAZ, SPGY, and TSPY
This test is done by doing PCR test on the blood
