BRCA1 & 2 screening (blood NGS)

• Most people who develop breast cancer have no family history of the disease. However, if you do have a family history of breast cancer, ovarian cancer, or both, heredity could have played a role in the cancer’s development. Most inherited cases of breast cancer are associated with two abnormal genes:
  BRCA1 (Breast Cancer gene 1) or
  BRCA2 (Breast Cancer gene 2)
• Women who inherit a mutation, or abnormal change, in either of these genes — from their mothers or their fathers — have a much higher-than-average lifetime risk of developing breast cancer and ovarian cancer.
• Women with a BRCA1 or BRCA2 genetic mutation have up to a 72% risk of being diagnosed with breast cancer during their lifetimes (compared to 12-13% for women overall).
• These women’s risk of ovarian cancer is also increased. Abnormal BRCA1 or BRCA2 genes are found in 5-10% of all breast cancer cases in the United States. Other types of inherited gene abnormalities are less common.